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Little discernable damage and very little histopathologic changes. Retrograde axoplasmic transport to the spinal cord.ĩ The virus reaches the brain and a wide disseminated encephalitis develops. Virus attaches at neuromuscular junctions via the acetylcholine receptor. However, since it is not always obvious how long an animal had been dead, the take-home message for the kids is to stay away from dead animals.ħ Girl with ulcerating lymphadenitis due to tularemia, Kosovo, April Image from CDC website: ( Ulceroglandular diseaseĨ Pathogenesis Exact pathogenic mechanisms are not fully understood.įollowing the bite or a lick of a rabid animal, local multiplication takes place in striated muscles. The saliva from animals that have been dead for a while is not infectious. Note: Once an animal dies, the rabies virus does not survive for very long under most environmental conditions. Unusual modes of transmission (inhalation, aerosoles, ingestion, and corneal and other transplants).Ħ Does everyone know what saliva is? Spit, drool.Ĭan anyone tell me what is on the boy’s blanket? A bat! UGGGGGH! Does everyone know what saliva is? Spit, drool. Rabies can be transmitted by moisture droplets in the air. Bites or licks of a rabid animal transmit rabies. It is bullet shaped, enveloped and has a diameter of 75X180 nm.Ĥ Rabies Virus G, M, L, N, and NS Proteinsĥ transmission Rabies is transmitted by rabid animals that have the virus in their saliva. Rabies belongs to the genus lyssa virus (rabies in Greek means mad or frenzy). Rabies is thought to be responsible for the origin of vampire legends (bats, biting, hypersexuality are associated with rabies).ģ Rhabdoviridae: A large number of member viruses that are serologically unrelated. The method of transmission of rabies was not recognized until 1804.
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and in ancient Greece, where it was described by Aristotle. The disease was recognized in Egypt before 2300 B.C. Presentation on theme: "Rabies."- Presentation transcript:Ģ Rabies is the most lethal of all infectious diseases.Įven the most extreme modern medical interventions are usually not successful.